FIGURE 1 from The FKBP51s Splice Isoform Predicts Unfavorable Prognosis in Patients with Glioblastoma

GBM TME analysis clusters two groups that differ in TAM composition. A, The subjects were divided into two groups using the Ward hierarchical clustering method based on the variable parameters measured in the TME (top heat map). The data from PB (bottom heat map) were not used for clustering, they followed the separation of TME data. Age, gender, HLA-DR tumor, FKBP51s tumor, PD-L1 tumor, and % of total infiltrating CD14 are reported as annotations of the heat map. B, Values of TME immunophenotype measured for each cluster are reported as box plots. C, Values of PB immunophenotype are reported as box plots. The P values of statistical difference tests are shown. *, P < 0.05; **, P < 0.01; ***, P < 0.001; ****, P < 0.0001.