Granulomatous Inflammation of the Skull Base: A Rare Case of Mycobacterium tuberculosis in the United States

The differential for an ill‐defined, bone‐destructive, granulomatous lesion of the skull base includes malignancy, as well as autoimmune and infectious processes. Suspicion for tuberculosis of the skull base in high‐risk patients is particularly necessary given the difficulty to culture on standard cultures, need for specific and prolonged antibiotic therapy, and dire morbidity if not diagnosed and treated in a timely manner. Repeat biopsies and cultures were necessary to diagnose this case of Mycobacterium tuberculosis of the skull base after initial biopsy was non‐diagnostic. Laryngoscope , 134:4023–4027, 2024