Cancer remains the leading cause of death worldwide, even in the face of enormous research and clinical efforts. These have yielded some promising therapies; however, they are neither broadly effective nor affordable. One of the most valuable new treatment classes has been immunotherapies, including vaccines. The different types of cancer vaccines and their characteristics, along with their contributions and shortfalls are summarized here. A more effective and significantly less expensive alternative to personalized therapeutic vaccines is proposed here to be an off-the-shelf, prophylactic one. However, knowing what antigens a future tumor will present has been considered impossible. The discoveries and technologies that together enable the identification of these types of vaccine components are described. A pre-made, preventative cancer vaccine has recently shown efficacy in a canine clinical trial. The path is opening for the development of effective vaccines to prevent cancers in people worldwide.
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Kathryn Sykes (2024) studied this question.
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