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Guideline review reports malignancy risk estimates in soft tissue tumors, highlighting unaddressed interobserver reproducibility across diagnostic categories.
In 2024, the World Health Organization (WHO) is scheduled to publish the WHO Reporting System for Soft Tissue Cytopathology (WHORSSTC). This system establishes categories with well-defined definitions, criteria, and estimated risks of malignancy (ROMs) for soft tissue tumors. The estimates of ROM are based on a relatively small number of published studies. Interobserver reproducibility is not addressed in the reporting system even though reproducibility of a reporting system is highly important.
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Layfield et al. (2024) studied this question.
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