The biological activity of resveratrol (3,5,4’-trihydroxy-trans-stilbene) has been the subject of extensive study in the treatment of various diseases due to its anti-inflammatory, antioxidant and anticancer activities, as well as its minimal toxicity and side effects. It has been widely accepted that resveratrol also has antiviral activities. In this mini-review, we summarize resveratrol’s antiviral mechanisms. Since viral infections are often accompanied by inflammation, the TLRs/NF-κB signaling pathways are key and common molecular mechanisms for resveratrol to exert anti-inflammatory and antiviral effects.
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Dos Santos WM (2024) studied this question.
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