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May 9, 2024Neurology and TherapyOpen Access

Additional Results from Two Randomized, Placebo-Controlled Trials of Stiripentol in Dravet Syndrome Highlight a Rapid Antiseizure Efficacy with Longer Seizure-Free Periods

Renzo Guerrini Laurent Chancharme B Serraz Catherine Chiron

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Abstract

The efficacy of stiripentol in Dravet syndrome children was evidenced in two randomized, double-blind, placebo-controlled, phase 3 studies, namely STICLO France (October 1996-August 1998) and STICLO Italy (April 1999-October 2000), but data were not fully exploited at the time.

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Guerrini et al. (2024) studied this question.

synapsesocial.com/papers/68e6ad90b6db64358762f319 https://doi.org/10.1007/s40120-024-00623-8

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