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May 8, 2024Alzheimer s & DementiaOpen Access

Antidepressant exposure and long‐term dementia risk in a nationwide retrospective study on US veterans with midlife major depressive disorder

Jaime Ramos‐Cejudo June K. Corrigan Chunlei Zheng Kaitlin N. Swinnerton Sean Jacobson Jennifer La Rebecca A. Betensky Ricardo S. Osorio Sharon Madanes Nunzio Pomara Dan V. Iosifescu Mary T. Brophy Nhan Do Nathanael R. Fillmore

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Abstract

The use of antidepressants in major depressive disorder (MDD) has been reported to influence long-term risk of Alzheimer's disease (AD) and AD-related dementias (AD/ADRD), but studies are conflicting.

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Ramos‐Cejudo et al. (2024) studied this question.

synapsesocial.com/papers/68e6b01bb6db64358763163c https://doi.org/10.1002/alz.13853

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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