Fink, M\'esz\'aros and St.Dizier showed that the Schubert polynomial Sw(x) is zero-one if and only if w avoids twelve permutation patterns. In this paper, we prove that the Grothendieck polynomial Gw(x) is zero-one, i.e., with coefficients either 0 or ±1, if and only if w avoids six patterns. As applications, we show that zero-one homogeneous Grothendieck polynomials are Lorentzian, partially confirming three conjectures of Huh, Matherne, M\'esz\'aros and St.Dizier. Moreover, we verify several conjectures on the support and coefficients of Grothendieck polynomials posed by M\'{e}sz\'{a}ros, Setiabrata and St.Dizier for the case of zero-one Grothendieck polynomials.
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Chen et al. (2024) studied this question.
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