Gym-Based Modified Powerlifting Exercises for People with Early Onset Parkinsons Disease: Study Protocol

Background Although powerlifting has been shown to increase strength and function in some adults, the safety and feasibility of powerlifting exercises modified for people with early onset Parkinson’s disease is not known. Methods People with early onset Parkinson’s disease (age <50 years) will be invited to engage in eight consecutive weeks of twice-weekly modified powerlifting exercises in a community gymnasium. The primary outcome is the feasibility of powerlifting exercises modified for people with early onset Parkinson’s disease, quantified by measures of safety, adverse events, adherence, access, and cost. Secondary outcomes include motor disability, quality of life, psychosocial status, and strength. Semi-structured interviews with participants and exercise trainers will capture experiences, beliefs, and attitudes towards this type of community-based strength training. Discussion Powerlifting may be beneficial for those with early onset Parkinson’s disease as it can improve muscle strength, coordination, and balance, and may have neuroprotective effects, potentially slowing down the progression of the disease. However, there is a need to first measure feasibility and safety of modified powerlifting in a small number of individuals before the efficacy can be tested in larger randomised controlled trials. Ethics and dissemination We will publish the findings in peer-reviewed journals and presentations at conferences. The consumer engagement council will guide communication of findings to individuals with early onset Parkinson’s disease, ensuring information is accessible and actionable for the target audience.