Total synthesis of brevianamides Y and Z demonstrates asymmetric methods in alkaloid chemistry.
Brevianamides X (1) and Y (2) are relatively new members of the bicyclo[2.2.2]diazaoctane alkaloid family, whose biosynthetic origins remain unresolved. We report the asymmetric total synthesis of (+)-brevianamides Y (2),...
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Nandy et al. (2025) studied this question.
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