May 2, 2024Cancer Research

Abstract PO4-17-06: Real World Data: A single institute experience with neoadjuvant endocrine therapy for ER+ breast cancer — clinical response rates, clinical predictors of response and long-term outcomes following breast conserving surgery

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Neoadjuvant endocrine therapy enabled over 92% of postmenopausal patients with ER-positive breast cancer to undergo successful breast-conserving surgery.
Tumour reduction averaged 71% across the cohort with a 59% overall response rate, while 10-year local recurrence fell to 7% with adjuvant radiotherapy.
Retrospective cohort analysis of 435 patients shows high Allred scores and early 6-week tumor shrinkage predict long-term clinical response to aromatase inhibition.

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Retrospective cohort study demonstrates high surgical conservation and disease control after neoadjuvant endocrine therapy in postmenopausal ER-positive breast cancer, highlighting the role of...

Cite This Study

Turnbull et al. (2024) studied this question.

synapsesocial.com/papers/68e6be8ab6db64358763e301 https://doi.org/10.1158/1538-7445.sabcs23-po4-17-06

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Implication

Retrospective cohort study demonstrates high surgical conservation and disease control after neoadjuvant endocrine therapy in postmenopausal ER-positive breast cancer, highlighting the role of...

Abstract PO4-17-06: Real World Data: A single institute experience with neoadjuvant endocrine therapy for ER+ breast cancer — clinical response rates, clinical predictors of response and long-term outcomes following breast conserving surgery

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Discussion

Implication

Cite This Study

Abstract PO4-17-06: Real World Data: A single institute experience with neoadjuvant endocrine therapy for ER+ breast cancer — clinical response rates, clinical predictors of response and long-term outcomes following breast conserving surgery

Key Points

Discussion

Implication

Cite This Study

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