A-67 | Assessment of BNP/Troponin Ratio in Patients Undergoing Cardiac Catheterization

Acute Coronary Syndrome and Acute decompensated Heart Failure can present with a similar symptoms and cn be difficult to differentiate. This study assesses correlation between the BNP/Troponin ratio and the presence of obstructive coronary artery disease on cardiac catheterization. A Single-center retrospective study of patients who were presented to the Emergency Department (ED) with symptoms suspicious of acute coronary syndrome (ACS). Peak BNP and hsTrop ratios (BNP/hsTrop) were recorded. Cardiac Catheterisation findings during the admission were recorded. The predictive value of BNP/hsTrop in obstructive CAD was compared using ROC curves. Results: Among the included 94 patients, 70 (7.7%) and 24 (7.7%) were categorized into an obstructive CAD and non-obstructive CAD. Hypertension (70.2% vs 20.2%, p=0.01) and history of percutaneous coronary angiography (PCI) (22.3% vs 1.1%, p = 0.03) were different between the two groups. The median BNP/hsTrop showed no significant differences between the obstructive CAD and non-obstructive groups. The AUC BNP/hsTrop was 0.6263 (95% CI: 0.4705 - 0.7821). The sensitivity of BNP/hsTrop was 0.431 and specificity was 0.882. The optimal cut-off value for BNP/hsTrop was 0.762. The ROC curve for BNP/hsTrop is displayed in Fig. 1, specific parameters of ROC curve analysis are also provided in Table 1. Conclusions: These findings suggest that the BNP-troponin ratio may be a valuable prognostic factor for diagnosing patients with and without obstructive coronary artery disease. Further multicenter trials are needed to explore and validate these results. E. Brennan, S. Saith, J. Marmur, A. Kahn, A. Khan, O. Adeniran, R. Syed, A. Waqas, T. Mucha, F. Amador, O. Akinti, H. Aiwuyo, Y. Ayinalem, A. Idres, Nothing to disclose.