Supplementary Figure 2 from Spatial Mapping of Hematopoietic Clones in Human Bone Marrow

Supplementary Figure 2. Targeted sequencing of BM fragments to identify somatic mutations. (A) Somatic mutations detected in 24 BM fragments selected for targeted sequencing, plotted at their location in the original sectioned specimen, color-coded by detected mutations and labeled with VAF. (B) Correlation of somatic mutations detected by sequencing and confirmed by ddPCR for JAK2 V617F (R2=0.99). (C) Correlation of somatic mutations detected by sequencing and confirmed by ddPCR for TET2 L1081* (R2=0.35).