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May 1, 2024Open Access

Supplemental Figure 7 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations

Malathi Kandarpa Dan R. Robinson Yi‐Mi Wu Tingting Qin Kristen Pettit Qing Li Gary D. Luker Maureen A. Sartor Arul M. Chinnaiyan Moshe Talpaz

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Abstract

Supplemental Figure 7. Differential gene expression in MF with Spleen size >7 cm vs <7 cm. Panel A is a heatmap of the differentially expressed genes, 554 genes upregulated in MF with large spleen and 303 genes downregulated. Panel B is Volcano plot showing log fold change and p value of the genes depicted in A. Panel C shows RNA enrichment analysis shows GO pathways that are down regulated (green) and upregulated (red) in MF with spleen enlargement.

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Kandarpa et al. (2024) studied this question.

synapsesocial.com/papers/68e6c4b3b6db6435876435d7 https://doi.org/10.1158/1078-0432.25728710.v1

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1Supplemental Figure 7 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations2024
2Supplemental Figure 5 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations2024
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Supplemental Figure 6 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations2024
Supplemental Figure 6 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations2024
Supplemental Figure 3 from Broad Next-Generation Integrated Sequencing of Myelofibrosis Identifies Disease-Specific and Age-Related Genomic Alterations2024