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May 1, 2024Endocrine PracticeOpen Access

#1697669 Lack of Tumor Localization on 68Ga DOTATATE PET/CT in Cushing's Syndrome due to Ectopic ACTH Secretion from Atypical Pulmonary Carcinoid Tumor

Mona Vahidi Rad Mona Vahidi Rad Samir M. Ahmed Krupa Doshi Aditi Kumar CRAIG JENKINS

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Abstract

Localization of ectopic ACTH secreting tumors causing Cushing's syndrome is essential for clinical management but is often difficult. 68Ga DOTATATE PET/CT is a sensitive and high-resolution diagnostic tool for localization of ectopic ACTH secreting tumors. 68Ga DOTATATE PET/CT can however be negative in less differentiated neuroendocrine tumors such as atypical carcinoids.

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Rad et al. (2024) studied this question.

synapsesocial.com/papers/68e6c5d9b6db6435876447b3 https://doi.org/10.1016/j.eprac.2024.03.119

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Role of 68Ga-DOTATOC Positron Emission Tomography in Locating Pulmonary Neuroendocrine Tumor Presenting with ACTH-Dependent Cushing’s Syndrome: A Case Report2025
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