Gonadotropinomas represent approximately 80% of non-functioning pituitary adenomas and 40% of all clinically recognized macroadenomas; However, these adenomas are usually clinically silent and cannot be distinguished from other non-functioning adenomas until after surgical removal of the pituitary tumor and immunohistochemical evaluation (IHC).
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Paz‐Ibarra et al. (2024) studied this question.
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