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May 1, 2024Journal of College of Physicians And Surgeons PakistanOpen Access

Predictors of Nucleos(t)ide Analogues Discontinuation Relapse: Hepatitis B Virus RNA versus Hepatitis B Surface Antigen

Shuo Wu Tao Li Feng Liu Dedong Yin Zhang Li Lei Wang

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Abstract

Objective: To compare the predictive value of hepatitis B virus (HBV) RNA and HBsAg quantification upon discontinuation of nucleos(t)ide analogues (NAs) therapy for clinical and virological relapse in chronic hepatitis B (CHB).Study Design: Observational study.

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Cite This Study

Wu et al. (2024) studied this question.

synapsesocial.com/papers/68e6c5d9b6db64358764496b https://doi.org/10.29271/jcpsp.2024.05.545

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1<scp>HBV RNA</scp> Predicts the Risk of Off‐Treatment Relapse in Chronic Hepatitis B Patients With <scp>NAs</scp> Therapy: A Systematic Review and Meta‐AnalysisSystematic Review · 2026 · 1 citations
2Optimizing off-treatment outcome predictions: The potential of time-varying HBcrAg and the need for more research2024
3Long-term hepatitis B surface antigen kinetics after nucleos(t)ide analog discontinuation in patients with noncirrhotic chronic hepatitis B2024
4Determinants of <scp>HBsAg</scp> Loss After Nucleos(t)ide Discontinuation in a Prospective Cohort of <scp>HBeAg</scp>‐Negative Caucasian Patients2025 · 3 citations
5Utility of a High-Sensitivity HBV RNA Assay for Monitoring HBV Carriers Receiving Nucleos(t)ide Analogue TherapyOriginal Research · 2026

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Evaluation of chronic hepatitis B patients who voluntarily discontinued oral antiviral therapy: is there an answer to the controversial topic?2024
High end‐of‐treatment hepatitis B core‐related antigen levels predict hepatitis flare after stopping nucleot(s)ide analogue therapy2024
Association of baseline HBcAg and HBV DNA with persistent detectability of HBV RNA during NA therapy2026

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