Clinical, Laboratory and Radiological Profile of Patients With Liver Abscess an Observational Study

Background:About two-thirds of liver abscess cases are due to amoebic etiology in the developing countries, but most abscesses are of pyogenic etiology in developed nations. In tropical countries like India, LAis a common problem and remains a diagnostic and therapeutic challenge for the treating physician. India is the home to several million people affected by Entamoeba histolytica, the causative organism of amoebic liver abscess (ALA). Due to the increasing trend of alcoholism, diabetes mellitus, compromised immune status, this problem is of paramount signicance as it may lead to a moribund state. Due to the advancement in imaging modalities, safer methods to treat liver abscesses are slowly evolving, especially since the past 20 years. Methods:Sample size: 50 cases(n=50). Selection of patients: patients admitted to Medical Wards of Government General Hospital, Kakinada with a conrmed diagnosis of LIVER ABSCESS were taken up for the study and followed until discharge from the hospital. Data collection: Data was collected by a pre-tested questionnaire. Data was collected from all the study population by direct interview after getting informed written consent from them. Data analysis: Data analysis was performed both manually and by using a computer. Calculated data were arranged systematically, presented in various tables and gures, and statistical analysis was made to evaluate the objectives of this study using SPSS software. Results:The present study included 50 patients(n=50) presented to Government General Hospital, Kakinada, who were diagnosed with liver abscess. Out of the 50 patients, 48 were men, and 2 were women.The youngest patient in this study is 22 years old, and the most aged 60 years of age. Conclusion:Etiological analysis of pus revealed anchovy sauce appearance in 72% cases and purulent pus in 28% of cases. Pus culture revealed 72% were sterile and 28% having a bacterial culture. Among the bacterial culture, Escherichia coli had the highest incidence of 12%, followed by Klebsiella and Staphylococcus aureus. Treatment constituted medical therapy and needle aspiration. Empirical treatment forming amoebicidal and antibiotics were started and modied if deemed necessary after etiological diagnosis. Most of the patients with solitary liver abscess needed a single ultrasound guided aspiration, whereas multiple liver abscess patients required more than one aspiration. . Good results were obtained by this method.The average hospital stay was 10.2 days. There was no mortality in this study.