Extrapancreatic Pseudopapillary Neoplasm Arising From the Mesentery, Masquerading as a Mesenteric Cyst – A Case Report

Background: Methods: Solid Pseudopapillary Neoplasms of the Pancreas are rare entities, and extrapancreatic origin of SPN are even rarer. (2) We present a case of a 30-year-old female with a slow growing abdominal mass, who underwent exploratory laparotomy owing to the clinical suspicion of a mesenteric cyst. Intraoperatively, there was a nodular growth arising from the mesentery, which on histopathologic exam showed sheets of small round cells arranged in patterns of papillae and pseudopapillae, and on IHC, these cells were positive for β-Catenin, conrming the diagnosis of Solid Pseudopapillary Neoplasms of the Pancreas. (3) There are 50 reported cases of Ext Conclusion: rapancreatic SPN, with only one other documented case arising from the mesentery, in the English literature. Although Pancreatic SPNs have low malignant potential, Extrapancreatic SPNs have been observed to have higher metastatic potential and recurrence rates, hence excision is recommended.