Comparative Study on the Efficacy of Certain Drugs Against Helminthiasis of Sheep in the Aktobe Region

Gastrointestinal Strongylata are the most common among all helminths of sheep, the invasion prevalence of which often reaches 90% or more. They cause significant economic damage. Our research purpose is to study the epizootic situation on gastrointestinal strongylatosis in IE Altyn, the Aktobe Region, and to determine the anthelmintic efficacy, in a comparative aspect, of various drugs from different classes of chemical compounds against gastrointestinal strongylatosis of sheep. The invasive rate in animals was determined by the Fulleborn method. The number of helminth eggs was calculated in 1 gram of faeces using a VIGIS camera. The gastrointestinal Strongylata genus in sheep was identified based on the morphological structure of infective larvae after being cultivated according to P. F. Polyakov. The anthelmintic efficacy was determined by a standardized method of the "control test" type. The sheep in IE Altyn were infected with five genera of gastrointestinal strongylates: Nematodirus spр., Ostertagia spр., Cooperia spр., Haemonchus spр., and Trichostrongylus spр. The prevalence in the sheep of gastrointestinal strongylates was 87.7% in average in IE Altyn, and the invasion intensity was 54.3±4.6 eggs/g. The anthelmintic efficacy of Alvet-suspension at a dose of 5 mg/kg, ivermek, 0.2 mg/kg, and levamisole, 7.5 mg/kg, was determined by the AS against strongylatosis of the digestive tract of sheep. Ivermek showed the greatest efficiency.