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April 24, 2024International Journal of Molecular SciencesOpen Access

The Immune Response of OAS1, IRF9, and IFI6 Genes in the Pathogenesis of COVID-19

Malena Gajate-Arenas Ingrid Fricke-Galindo Omar García-Pérez Angélica Domínguez-de-Barros Gloría Pérez-Rubio Roberto Dorta‐Guerra Ivette Buendía-Roldán Leslie Chávez‐Galán Jacob Lorenzo‐Morales Ramcés Falfán‐Valencia Elizabeth Córdoba-Lanús

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Abstract

COVID-19 is characterized by a wide range of clinical manifestations, where aging, underlying diseases, and genetic background are related to worse outcomes. In the present study, the differential expression of seven genes related to immunity,

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Cite This Study

Gajate-Arenas et al. (2024) studied this question.

synapsesocial.com/papers/68e6dc24b6db64358765822e https://doi.org/10.3390/ijms25094632

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Overexpression of OAS Genes in Severe COVID-19: A Cross-Sectional Study of Hospitalized Patients Infected with Delta and Omicron VariantsCross-Sectional Study · 2026
2Modulation of TLR7, TYK2 and OAS1 expression during SARS-CoV-2 infection2025 · 1 citations
3Expression level of interferon-stimulated genes PKR, OAS1, MX1, and ISG15 in peripheral blood mononuclear cells of COVID-19 patients: A retrospective study2024 · 3 citations
4Rewired type I IFN signaling is linked to age-dependent differences in COVID-192025 · 4 citations
5Identification of immune-related hub genes and potential molecular mechanisms involved in COVID-19 via integrated bioinformatics analysis2024

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Innate immunogenetic synergy between KIR and Neanderthal-derived OAS variants predicts COVID-19 outcomes2026

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