Preclinical analysis observes biological behavior changes in mesenchymal stem cells under high glucose and severe hypoxia, highlighting stress factors that may alter cell therapies.
Mesenchymal stem cells (MSCs) have been extensively studied for therapeutic potential, due to their regenerative and immunomodulatory properties. Serial passage and stress factors may affect the biological characteristics of MSCs, but the details of these effects have not been recognized yet.
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Almahasneh et al. (2024) studied this question.
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