Antimicrobial activities of some species in Asteraceae and Lamiaceae families from Türkiye

The study aimed to investigate the antimicrobial activities of the species belong to Asteraceae and Lamiaceae families collected from Çorum, Eskişehir and Kütahya provinces in Türkiye on Gram (+) and Gram (-) bacterial strains using EUCAST disc diffusion method. Ethanol (96%) and Ciprofloxacin (5mcg) were used as negative and positive controls, respectively. All plant extracts produced inhibition zones on S. aureus and E. faecalis ranged between 4.67-14.33 mm and 21.67-23.67 mm respectively. The variance in the antimicrobial activities of the plant extracts was significant between groups according to ANOVA. L. angustifolia samples collected from Eskişehir and Kütahya gave zone diameters close to the positive control on S. aureus and E. faecalis. It was determined that E. coli was the most resistant and S. aureus and E. faecalis were the most sensitive microorganisms in this study. L. angustifolia-E, M. piperita and S. officinalis were the species whose extracts were coming front with their high antimicrobial activities. Pearson's correlation analyses displayed that the antimicrobial activity on E. coli was correlated positively and negatively with altitude and latitude respectively, while on E. faecalis was positively correlated with altitude and negatively correlated with latitude and longitude. In conclusion, the variations in the antimicrobial activities of the secondary metabolites found in the extracts of medicinal aromatic plants are important and, although the quantity, quality, and diversity of these compounds are determined according to the genotypes of plants, the environmental conditions in which the plants grow might have an impact on these differences.