Introduction Inverted papillomas (IP) are benign epithelial growths in the nasal cavity and the paranasal sinuses with a high tendency to recur. Despite their benign nature, IP"s may grow locally invasive and turn malignant in 12% of cases. A recently described distinct histological entity of squamous cell carcinoma is defined by the presence of a DEK:AFF2 fusion. The case highlights the significance of investigating recurrent IP cases for this specific gene fusion.
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Moniri et al. (2024) studied this question.
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