A Mn‐electrocatalytic ring‐opening azidation of tert ‐cyclobutanols has been developed. The regioselective method is applicable for the azidation of a diverse array of cyclobutanols to provide practical γ ‐azido ketones in 23–91% yields under chemical oxidants‐free reaction conditions. Detailed mechanistic studies suggest the process of Mn‐mediated alkoxy radical generation followed by β ‐scission to form carbon‐centered radical species is possibly involved in this transformation.
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Gao et al. (2024) studied this question.
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