The effects of a novel, continuous disinfectant technology on methicillin-resistant Staphylococcus aureus (MRSA), fungi, and aerobic bacteria in 2 separate intensive care units in 2 different states: An experimental design with observed impact on health care associated infections (HAIs)

BackgroundHospitals are exposed to abundant contamination sources with limited remediation strategies. Without new countermeasures or treatments, the risk of hospital-associated infections will remain high. This study explored the impact of advanced photohydrolysis (AP) continuous disinfection technology on hospital environmental bioburden.MethodsTwo acute care Intensive Care Units in different locations (i.e., Kentucky, Louisiana) during different time periods. Locations were sampled every 4 weeks for 4 months for colony forming units (CFUs) of methicillin resistant Staphylococcus aureus (MRSA) and fungi on surfaces and floors and fungi and aerobic bacteria in air.ResultsAt both sites, surface testing showed greater than 98% reduction in mean fungi and MRSA CFUs. Floor results had reductions by more than 96% for fungi and MRSA at both sites. Aerobic bacterial air and fungal CFUs had reductions up to 72% and 89%, respectively. HAIs declined 70% when post activation data was compared to pre-activation data.DiscussionThe continuous nature of the AP decontamination, its ability to be used in occupied rooms, and its independence of human resources, provides an innovative intervention for complex healthcare environments.ConclusionsThis study is on the pioneering edge of demonstrating that continuous decontamination can reduce surface, floor, and air contamination and thereby reduce acquisition of HAIs.