Mp68-12 Association Between Prostate Cancer Detection Rate and Year of Prostate Biopsy

You have accessJournal of UrologyProstate Cancer: Epidemiology & Natural History II (MP68)1 May 2024MP68-12 ASSOCIATION BETWEEN PROSTATE CANCER DETECTION RATE AND YEAR OF PROSTATE BIOPSY YoungJun Uhm, Woojin Bang, Myungsun Shim, Cheol Young Oh, Sun Il Kim, Hwanik Kim, and Jin Seon Cho YoungJun UhmYoungJun Uhm , Woojin BangWoojin Bang , Myungsun ShimMyungsun Shim , Cheol Young OhCheol Young Oh , Sun Il KimSun Il Kim , Hwanik KimHwanik Kim , and Jin Seon ChoJin Seon Cho View All Author Informationhttps://doi.org/10.1097/01.JU.0001008744.60568.e8.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Among male cancers, prostate cancer incidence has increased rapidly from 5th in 2008 to 3rd in 2020. It is assumed that the prostate cancer detection rate will increase accordingly, authors investigated whether there was a plausible relationship between the year the prostate biopsy was performed and the prostate cancer detection rate. METHODS: The medical records of 1628 patients who underwent prostate biopsy between 2008 and 2022, for each even-numbered year, were retrospectively reviewed. The primary outcome was the prostate cancer detection rate, and the secondary outcome was to determine whether the prostate cancer detection rate was significantly associated with the year of prostate biopsy and other clinical factors. RESULTS: When comparing baseline clinical factors between patients who underwent prostate biopsy by year, there were significant differences in age at the time of biopsy (p=0.017) and number of biopsy cores (p<0.001), and no significant differences in other clinical factors. Prostate cancer detection rates ranged from 30.2% to 53.1% and were significantly positively correlated with the year of biopsy (R2=0.839, p<0.001). Subgroup analysis according to PSA level (≤10, over 10 to 20, >20ng/mL) showed detection rates of 13.5 - 40.9%, 29.2 - 62.2%, 73.3 - 92.6%, respectively. There were also significant positive correlations between year of biopsy and prostate cancer detection rate (R2=0.769, p=0.004/R2=0.843, p=0.001/R2=0.810, p=0.002). CONCLUSIONS: The prostate cancer detection rate tends to increase with each successive year of prostate biopsy. This increasing trend seems to be particularly pronounced in patients with relatively older age, higher PSA and higher ISUP grade group. These findings need to be validated in multicenter prospective studies and various cohorts. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e1112 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information YoungJun Uhm More articles by this author Woojin Bang More articles by this author Myungsun Shim More articles by this author Cheol Young Oh More articles by this author Sun Il Kim More articles by this author Hwanik Kim More articles by this author Jin Seon Cho More articles by this author Expand All Advertisement PDF downloadLoading ...