Mp28-05 What Do Patients With Peyronie's Disease Expect From Therapy? A Prospective Multi-Center Study

You have accessJournal of UrologySexual Function/Dysfunction: Peyronie's Disease (MP28)1 May 2024MP28-05 WHAT DO PATIENTS WITH PEYRONIE'S DISEASE EXPECT FROM THERAPY? A PROSPECTIVE MULTI-CENTER STUDY Lukas Schaefer, Jann Cremers, Bahne Witschel, Victor Schuettfort, Timo O. Nieder, Frederik Koenig, Malte W. Vetterlein, Philipp Gild, Margit Fisch, Roland Dahlem, Margit Fisch, Sabine Kliesch, and Armin Soave Lukas SchaeferLukas Schaefer , Jann CremersJann Cremers , Bahne WitschelBahne Witschel , Victor SchuettfortVictor Schuettfort , Timo O. NiederTimo O. Nieder , Frederik KoenigFrederik Koenig , Malte W. VetterleinMalte W. Vetterlein , Philipp GildPhilipp Gild , Margit FischMargit Fisch , Roland DahlemRoland Dahlem , Margit FischMargit Fisch , Sabine KlieschSabine Kliesch , and Armin SoaveArmin Soave View All Author Informationhttps://doi.org/10.1097/01.JU.0001008872.42208.7a.05AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Little is known about patients' pre-treatment expectations in Peyronie's disease (PD). To evaluate in detail patients' expectations of conservative therapy and surgery. METHODS: This multi-center study prospectively enrolled 317 PD patients, who were scheduled to receive conservative therapy or surgery between 2019 and 2022 at the Department of Urology of the University Medical Center Hamburg-Eppendorf, and the Center of Reproductive Medicine and Andrology, University Medical Center Muenster, both Germany. The primary end-point was patients' pre-treatment expectations of conservative therapy and surgery, measured with the Stanford Expectations of Treatment Scale (SETS). Secondary end-points included patient-reported psychological and physical symptoms, penile pain, symptom bother and erectile function, measured with the Peyronie's Disease Questionnaire (PDQ) and International Index of Erectile Function Erectile Function Domain (IIEF-EF). RESULTS: In total, 239 (75%) and 78 (25%) patients were scheduled for conservative therapy and surgery, respectively. Patients undergoing surgery had higher positive and negative mean SETS expectations scores (14 vs. 11, p<0.001; 9.6 vs. 6.0, p<0.001). In multivariable analysis, surgery was an independent predictor of positive and negative patients' pre-treatment expectations (all p≤0.001). In thematic analysis, patients undergoing surgery emphasized distinct themes of pre-treatment expectations. Patients undergoing surgery had higher mean PDQ symptom bother as well as higher psychological and physical symptom scores (14 vs. 10, p<0.001; 9.2 vs. 7.1, p=0.001). There were significant positive correlations between SETS negative expectation score and PDQ symptom bother (|ρ|=0.25; p<0.001) as well as PDQ psychological and physical symptoms score, respectively (|ρ|=0.21; p=0.001). CONCLUSIONS: PD patients expect both more benefit and more harm from surgery. In addition, patients undergoing surgery have more psychological and physical symptoms and more symptom bother. To set realistic expectations, it is of pivotal importance to assess patients' expectations before starting treatment. Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e473 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Lukas Schaefer More articles by this author Jann Cremers More articles by this author Bahne Witschel More articles by this author Victor Schuettfort More articles by this author Timo O. Nieder More articles by this author Frederik Koenig More articles by this author Malte W. Vetterlein More articles by this author Philipp Gild More articles by this author Margit Fisch More articles by this author Roland Dahlem More articles by this author Margit Fisch More articles by this author Sabine Kliesch More articles by this author Armin Soave More articles by this author Expand All Advertisement PDF downloadLoading ...