Mp50-16 Increased Risk of Genitourinary Disorders in Neurodivergent Children

You have accessJournal of UrologyPediatrics III (MP50)1 May 2024MP50-16 INCREASED RISK OF GENITOURINARY DISORDERS IN NEURODIVERGENT CHILDREN Sarah Strausser, Raidizon Mercedes, and Susan M. MacDonald Sarah StrausserSarah Strausser , Raidizon MercedesRaidizon Mercedes , and Susan M. MacDonaldSusan M. MacDonald View All Author Informationhttps://doi.org/10.1097/01.JU.0001008684.57262.97.16AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Children with diagnoses of neurodivergence may have delayed toilet training or be more prone to bladder and bowel dysfunction. We sought to query if any genitourinary (GU) sequelae were associated with a diagnosis of neurodivergence. METHODS: The TriNetX database was queried for children under 18 years of age with neurodivergent conditions using the following Current Procedural Terminology (CPT) codes: Autistic Disorder F84.0, Asperger's Syndrome F84.5, Pervasive Developmental Disorders F84, Oppositional Defiant Disorder F91.3, Conduct Disorders F91, Attention Deficit Hyperactivity Disorder F90.0-F90.8, Tourette's Disorder F95.2, Other Voice and Resonance Disorders R49.8, Obsessive Compulsive Disorder F42, and Obsessive Compulsive Personality Disorder F60.5. Patients under the age of 18 years old without a diagnosis of neurodivergence were classified as the control group. We cross-referenced for the incidence of GU disorders using the following diagnosis codes: UTI N39.0, Nocturnal enuresis N39.44, Vesicoureteral-reflux N13.7, and Hydronephrosis N13.30. Males and females in the neurodivergent cohort were compared to the control group. RESULTS: A total of 522,789 males and 233,299 females with neurodivergent diagnoses were identified. Figure 1 summarizes the odds ratios of pediatric GU diagnoses in neurodivergent children stratified by sex. The odds ratio for nocturnal enuresis was 5 times that of the control population for both males and females (p<0.01). The odds ratio for UTI was double for females and nearly so for males (p<0.01). Rates of vesicoureteral reflux and hydronephrosis were also higher in the neurodivergent population for both males and females (p<0.01). Figure 2 summarizes the distribution of GU disorders in those with a diagnosis of neurodivergence compared to the control group without respect to sex. CONCLUSIONS: Children with neurodivergent diagnoses are likely at increased risk for GU disorders. Further research is warranted. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e838 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Sarah Strausser More articles by this author Raidizon Mercedes More articles by this author Susan M. MacDonald More articles by this author Expand All Advertisement PDF downloadLoading ...