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April 12, 2024Nephrology Dialysis TransplantationOpen Access

Both partial inactivation as well as activation of NF-κB signaling lead to hypertension and chronic kidney disease

Xiaotan Zhang Guang Wang Ming Li Yunjin Li Xin Luo Yvonne Liu Xiaoli Zhang Johann-Georg Hocher Bernhard K. Krämer Berthold Hocher Xuesong Yang

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Abstract

Activation of NF-κB-signalling is key in the pathogenesis of chronic kidney diseases (CKD). However, a certain level of NF-κB activity is necessary to enable tissue repair.

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Cite This Study

Zhang et al. (2024) studied this question.

synapsesocial.com/papers/68e6f5edb6db643587670080 https://doi.org/10.1093/ndt/gfae090

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