Comparative genomic analysis reveals UV light signatures and high tumor mutation burden in conjunctival squamous cell carcinoma cohorts, highlighting potential etiopathogenic treatment targets.
Conjunctival squamous cell carcinoma (conjSCC) is more prevalent and aggressive in sub-Saharan African countries compared with the rest of the world. This study aims to compare the genomic, immunophenotypic, and histologic features between patients from the United States and Ethiopia, to identify etiopathogenic mechanisms and unveil potential treatment strategies.
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Gleber‐Netto et al. (2024) studied this question.
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