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April 10, 2024Asian Journal of SurgeryOpen Access

The safety and effectiveness of prophylactic hyperthermic intraperitoneal chemotherapy in patients with pathological T3-4 locally advanced colon cancer

Taiwei Mo Xiaofeng Wen Tuo Hu Zongjin Zhang Yaqian Shi Yongle Chen Haidong Xiang Junhua Huang Zhenyu Xian Xiaowen He

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Abstract

The safety and effectiveness of prophylactic hyperthermic intraperitoneal chemotherapy (HIPEC) in pathological T3-4 locally advanced (pT3N + M0 and pT4NxM0) colon cancer (CC) patients with radical resection need further study.

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Mo et al. (2024) studied this question.

synapsesocial.com/papers/68e6fa9eb6db6435876754d9 https://doi.org/10.1016/j.asjsur.2024.03.143

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Time to define the role of hyperthermic intraperitoneal chemotherapy (HIPEC) in <scp>T4</scp> colon cancerOriginal Research · 2026
2Efficacy and safety of intraoperative hyperthermic intraperitoneal chemotherapy for locally advanced colorectal cancer (HIPECT4): final analysis of randomized clinical trialRCT · 2025 · 2 citations
3Hyperthermic intraperitoneal chemotherapy in colorectal cancer2024 · 22 citations
4[Value and controversy of prophylactic hyperthermic intraperitoneal chemotherapy in locally advanced colorectal cancer].2025 · 1 citations
5Pilot Study: Prophylatic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Colorectal Cancers at High Risk of Developing Peritoneal Metastases in a Tertiary Asian Centre2024

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Safety analysis of intraperitoneal hyperthermic chemotherapy in the treatment of gastrointestinal cancer: a systematic review and meta-analysis2026
Safety and preliminary efficacy of Intraoperative hyperthermic intraperitoneal chemotherapy (HIPEC) in 100 pediatric patients with solid tumors: a retrospective study2025

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