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April 9, 2024Neurology

The Multi-kinase Inhibitor AZD4547 Reduces Inflammation and Neurodegeneration, and Enhances Remyelination in a Mouse Model of Multiple Sclerosis (P7-6.008)

Kian Shirvanchi Fynn Gurski Vinothkumar Rajendran R. Rajendran Fevronia‐Foivi Megalofonou Christine Stadelmann Srikanth Karnati Martin Berghoff

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Abstract

To characterise the effects of multi-kinase inhibition of FGFR, VEGFR2 and CSF1R on the disease course, inflammation and degeneration in EAE.

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Shirvanchi et al. (2024) studied this question.

synapsesocial.com/papers/68e6fcb5b6db643587676eab https://doi.org/10.1212/wnl.0000000000205039

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