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April 9, 2024Neurology

Shorter Time to Treatment with Diazepam Nasal Spray Is Associated with Faster Seizure Termination: A Subpopulation Analysis (P9-1.001)

Danielle A. Becker Randa Jarrar John M. Stern Adrián L. Rabinowicz Enrique Carrazana

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Abstract

To investigate temporal patterns of seizure clusters treated with diazepam nasal spray (Valtoco®) in adult and pediatric subpopulations and in patients with ≥20 recorded seizure clusters.

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Cite This Study

Becker et al. (2024) studied this question.

synapsesocial.com/papers/68e6fdadb6db643587677e1b https://doi.org/10.1212/wnl.0000000000205709

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Increased interval between seizure clusters across time in pediatric patients treated with the immediate‐use seizure medication diazepam nasal sprayEarly-Phase Clinical Trial · 2026
2Diazepam nasal spray administration is effective to control seizure clusters irrespective of time of day2024 · 1 citations
3Outcomes of out‐of‐hospital treatment of impending tonic–clonic status epilepticus with diazepam nasal spray: A retrospective combined cohort analysisCohort Study · 2026
4Safety and Local Tolerability of Diazepam Nasal Spray for Children With Epilepsy Aged 2-5 Years: Final Results of a Phase 1/2a TrialEarly-Phase Clinical Trial · 2026
5Safety and effectiveness of diazepam nasal spray in male and female patients: Post hoc analysis of data from a phase 3 safety study2024 · 5 citations

More related papers

Evaluating Bioequivalence of a New, Higher-Concentration Diazepam Nasal Spray for Seizure Clusters Compared with the Current Formulation in Healthy Adults2026
Safety and effectiveness of diazepam nasal spray in patients with Rett syndrome and seizure clusters: post hoc analyses from a long-term safety study and survey of severity and burden2026
Systematic statistical analysis of change in <scp>SEIzure interVAL</scp> with diazepam nasal spray supports this novel clinical endpoint for immediate‐use seizure medication2026

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