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April 9, 2024Neurology

Association of Rare NOTCH3 Variants with Prevalent and Incident Stroke and Dementia in the General Population (P8-4.003)

Pei Wang Ming Yao Jing Yuan Fei Han Fei‐Fei Zhai Dingding Zhang Lixin Zhou Jun Ni Yuanqiang Zhang Liying Cui Yi‐Cheng Zhu

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Abstract

This study aims to determine the associations of rare NOTCH3 variants with prevalent and incident stroke and dementia, as well as cognitive function changes.

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Cite This Study

Wang et al. (2024) studied this question.

synapsesocial.com/papers/68e6fdb8b6db64358767819f https://doi.org/10.1212/wnl.0000000000206089

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Association of Rare <i>NOTCH3</i> Variants With Prevalent and Incident Stroke and Dementia in the General Population2024 · 1 citations
2Analyses of NOTCH3 variants in Chinese patients with clinically diagnosed Alzheimer's disease and frontotemporal dementia2025
3<i>NOTCH3</i> Pathogenic Variant and Risk of Age-Related Macular Degeneration: Findings From the Taiwan Biobank and Small Vessel Disease RegistryRandomized Controlled Trial · 2026
4Clinical and neuroradiological spectrum of biallelic variants in NOTCH32024 · 15 citations
5Association of <i>NOTCH3</i> Variant Risk Category With 2-Year Clinical and Radiologic Small Vessel Disease Progression in Patients With CADASIL2024 · 14 citations

Clinical Impact of <scp>NOTCH3</scp> Variant Location After First Stroke in <scp>CADASIL</scp>2026
Plasma NOTCH3 and the risk of cardiovascular recurrence in patients with ischemic stroke2024
Pro‐Hemorrhagic Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy Associated with <i>NOTCH3</i> p.<scp>R75P</scp> Mutation with Low Vascular NOTCH3 Aggregation Property2024
Differences in Epilepsy Etiology, Type, Syndrome, and Severity Between Māori and Non-Māori-Non-Pasifika Children With Epilepsy in New ZealandNeurology · 2026
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