Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology

Kristiana Xhima; Julie Ottoy; Erin Gibson; Katherine Zukotynski; Christopher J.M. Scott; Ginelle Feliciano; Sabrina Adamo; Phillip H. Kuo; Michael Borrie; Howard Chertkow; Richard Frayne; Robert Laforce; Michael D. Noseworthy; Frank S. Prato; Demetrios J. Sahlas; Eric E. Smith; Vesna Sossi; Alexander Thiel; Jean‐Paul Soucy; Jean‐Claude Tardif; Maged Goubran; Sandra E. Black; Joel Ramirez

doi:10.1002/alz.13791

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Abstract

Cerebral small vessel disease (SVD) and amyloid beta (Aβ) pathology frequently co-exist. The impact of concurrent pathology on the pattern of hippocampal atrophy, a key substrate of memory impacted early and extensively in dementia, remains poorly understood.

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Xhima et al. (2024) studied this question.

synapsesocial.com/papers/68e70681b6db64358768050e https://doi.org/10.1002/alz.13791

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Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology

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Abstract

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Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology

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Abstract

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