Supplementary Figure 5 from Oncogenic Cells of Renal Embryonic Lineage Sensitive to the Small-Molecule Inhibitor QC6352 Display Depletion of KDM4 Levels and Disruption of Ribosome Biogenesis

Gene set enrichment analysis demonstrated significant downregulation of the REACTOME_EUKARYOTIC_TRANSLATION_INITIATION and REACTOME_PRC2_METHYLATES_HISTONES_AND_DNA pathways in QC6352-treated WiT49 cells and the REACTOME_EUKARYOTIC_TRANSLATION_INITIATION pathway in HEK293 cells.