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April 1, 2024The CRISPR Journal

Gene Editing in the Chagas Disease Vector Rhodnius prolixus by Cas9-Mediated ReMOT Control

Leonardo Lima Mateus Berni Jamile Mota Daniel Bressan Alison Henrique Ferreira Julio Robson Cavalcante Vanessa M. Macias Zhiqian Li Jason L. Rasgon Ethan Bier Helena Araujo

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Abstract

is currently the model vector of choice for studying Chagas disease transmission, a debilitating disease caused by

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Cite This Study

Lima et al. (2024) studied this question.

synapsesocial.com/papers/68e70d94b6db643587687310 https://doi.org/10.1089/crispr.2023.0076

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Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1<i>Streptococcus pyogenes</i> Cas9 ribonucleoprotein delivery for efficient, rapid and marker‐free gene editing in <i>Trypanosoma</i> and <i>Leishmania</i>2024 · 16 citations
2Effect of salivary <i>CYP4EM1</i> and <i>CYP4EM2</i> gene silencing on the life span of Chagas disease vector <scp> <i>Rhodnius prolixus</i> </scp> (Hemiptera, Reduviidae) exposed to sublethal dose of deltamethrinOriginal Research · 2021 · 11 citations
3Methodological Evaluation of a P2C-Based ReMOT CRISPR/Cas9 System in Aedes aegyptiOriginal Research · 2026
4Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegyptiOriginal Research · 2017 · 31 citations
5Engineered Promoter System Enables High-efficiency Transgenic CRISPR Editing in Malaria Transmitting Mosquito Anopheles sinensis2025

More related papers

An Accessible Intersectional Transgenic Single-Vector CRISPR/Cas9 Platform for Precise Gene Editing and Functional Analysis2024
Rp-vasa: a bona fide Primordial Germ Cell marker that drives embryonic expression in the Chagas disease vector Rhodnius prolixus2026
Co-expression of the AsCas12a ultra variant, a T7 RNA Polymerase and a cytosine base editor greatly increases transfection and editing rates in Leishmania species2024

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