Patient Demographics and Prognostic Factors of Skin Appendage Carcinoma: An Analysis of the NCDB

Background: Skin appendage carcinoma (SAC) is a rare malignancy with limited literature due to its low prevalence. This study explores demographic and prognostic factors for SAC in the United States. Methods: Data from the National Cancer Database (NCDB) were analyzed to identify factors affecting SAC mortality. Descriptive statistics and Cox regression analysis were employed. Results: SAC is slightly more common in males and frequently occurs in the face, scalp, and neck regions. Age and Charlson-Deyo comorbidity scores were significant prognostic factors, with older age and higher scores linked to decreased survival. Private insurance predicted better survival compared to Medicaid, Medicare, or no insurance. Conclusion: Individualized clinical interventions considering patient age, insurance status, and comorbidities are crucial. SAC does not exhibit disparities in survival based solely on race or socioeconomic status, but equitable access to care is essential for improving outcomes.