Real-world use of HIF-PH inhibitors and ESAs in non-dialysis-dependent CKD with anemia: insights from a Japanese database study

Q: What type of study is this?

This is a Cross-Sectional Study study.

Kiichiro Ueta; Manabu Ishii; Akira Oku; Kenji Arakawa; Kenichi Nishimura; Toshio Hashimoto; Takahiro Kuragano

doi:10.1080/03007995.2025.2570771

October 7, 2025Current Medical Research and OpinionOpen Access

Real-world use of HIF-PH inhibitors and ESAs in non-dialysis-dependent CKD with anemia: insights from a Japanese database study

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Key Points

HIF-PH inhibitors have been increasingly used in managing anemia associated with CKD in Japan since their introduction.
The study found a significant number of patients receiving treatment, revealing insights into clinical practice patterns.
Data were collected from a Japanese database, offering a detailed look at HIF-PH inhibitors usage in patients not on dialysis.
Findings may inform future guidelines and treatment strategies for anemia in CKD, emphasizing real-world applicability.

Implication

Database study reveals clinical usage of HIF-PH inhibitors and ESAs for anemia management in CKD patients, highlighting emerging trends.

Abstract

Background Hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitors were introduced for the treatment of anemia in chronic kidney disease (CKD) in Japan in 2020; however, data on their use in clinical practice remain limited.

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Cite This Study

Ueta et al. (2025) studied this question.

synapsesocial.com/papers/68e70dab90569dd607ee5ee6 https://doi.org/10.1080/03007995.2025.2570771

View Full Paper

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Real-world use of HIF-PH inhibitors and ESAs in non-dialysis-dependent CKD with anemia: insights from a Japanese database study

Key Points

Implication

Abstract

Discussion

Cite This Study

Real-world use of HIF-PH inhibitors and ESAs in non-dialysis-dependent CKD with anemia: insights from a Japanese database study

Key Points

Implication

Abstract

Discussion

Cite This Study

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