The diagnosis of paraneoplastic glomerulonephritis (PGN) is challenging and often delayed, which can lead to significant morbidity and mortality. Paraneoplastic glomerulonephritis is a rare complication of a malignant tumor, with glomerular lesions that are not directly related to tumor burden, invasion or metastasis, but are induced by products of tumor cells. PGN can be the initial presentation of renal cell carcinoma (RCC) or a sign of recurrence. The association of ANCA associated vasculitis with solid tumors has been sporadically reported, but cancers are frequently diagnosed after the initial diagnosis of vasculitis.
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Fuentes-Mendez et al. (2024) studied this question.
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