Mycophenolate mofetil (MMF) is a derivative of mycophenolic acid (MPA) that inhibits the control of T and B lymphocytes and the formation of antibodies and is one of the most effective immunosuppressants in kidney transplant recipients. It is known that MMF can directly cause local gastrointestinal toxicity, or that it can determine cell death by apoptosis and damage to the crypts through cytotoxic or immune-mediated mechanisms. We report a case of colitis caused by MMF.
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Moreira et al. (2024) studied this question.
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