Relationship Between Mesenteric Lymphadenitis and SIRS

Objectives: Mesenteric lymphadenitis is a condition characterized by inflammation of the lymph nodes in the mesentery.Systemic inflammatory response syndrome (SIRS) is a clinical response to a non-specific insult, which can be caused by various factors such as infection, trauma, burns, or other severe bodily stresses.The study aims to investigate the relationship between mesenteric lymphadenitis and SIRS, hospitalization, and treatment.Methods: This single-center retrospective cohort study was conducted.A total of 58 patients who presented to the emergency department with acute abdominal pain and were diagnosed with mesenteric lymphadenitis on computed tomography were evaluated.Results: A total of 58 patients (27 males and 31 females) with mesenteric lymph adenitis were included in the study.Fever of 37.5 °C and above was recorded in 5 patients (8.6%).Fourteen patients (24.1%) had leucocytosis.Twenty-four patients (41.4%) had elevated CRP.The mean CRP in this group was 15.2±14.1 mg/L.Tachycardia was detected in four patients (6.9%).Tachypnoea was recorded in 3 patients (5.2%).In our study, 12 patients (20.7%) fulfilled SIRS criteria.The most frequently met SIRS criteria in these mesenteric lymphadenitis patients were fever (n=5), white cell count (n=14), heart rate (n=4) and respiratory rate (n=3).In our study, the hospitalisation rate tended to be higher in the SIRS group (4/12 patients) compared to the non-SIRS group (1/46 patients). Conclusion:The rate of SIRS (+) was lower in patients diagnosed with mesenteric lymphadenitis.The group with SIRS (+) was more likely to accompany additional radiological comorbidity and hospitalization rates.The group with SIRS (+) was more likely to accompany additional radiological comorbidity and hospitalization rates.