Gene Therapy in Orofacial Pain – An Overview

Disorders involving the jaw, mouth, face, head, and neck are diagnosed, managed, and treated under the dental specialty known as orofacial pain (OFP). As the pathophysiology of OFPs is complex, evidence-based knowledge is essential for treating these illnesses effectively. Since OFP affects the affected individuals’ quality of life, it is crucial to treat patients with success. As a result of the inter-patient differences, treating OFP remains difficult even with the available therapy options. Gene therapy exhibits promising potential in bridging the gap between medicine and dentistry applications. Gene therapy’s dynamic treatment modalities have been developing quickly. Redesigning conventional methods to be more all-encompassing and preventive may eliminate the need for medication and surgery. Genes are sequences of complementary bases that carry the instructions needed to make proteins. One of the most accessible areas for the therapeutic application of gene therapy for various oral tissues is the oral cavity.