Supplemental Table 4 from Cytogenetic and Molecular Associations with Outcomes in Higher-Risk Myelodysplastic Syndromes Treated with Hypomethylating Agents plus Venetoclax

Alexandre Bazinet; Sai Prasad Desikan; Ziyi Li; Juan José Rodríguez‐Sevilla; Sangeetha Venugopal; Samuel Urrutia; Guillermo Montalban‐Bravo; Koji Sasaki; Kelly S. Chien; Danielle Hammond; Rashmi Kanagal‐Shamanna; Irene Gañán‐Gómez; Tapan M. Kadia; Gautam Borthakur; Courtney D. DiNardo; Naval Daver; Elias Jabbour; Farhad Ravandi; Hagop M. Kantarjian; Guillermo Garcia‐Manero

doi:10.1158/1078-0432.25515448

Key Points

Outcomes reveal significant differences in baseline characteristics between treated cohorts, highlighting potential therapeutic benefits.
Key findings include comparisons to a contemporary hypomethylating agents monotherapy cohort, underscoring treatment effects.
Analysis utilizes baseline characteristics from HMA-naïve patients with higher-risk myelodysplastic syndromes against a contemporary cohort for better insights into therapy outcomes.

Implication

Assessment compares outcomes in higher-risk myelodysplastic syndromes treated with hypomethylating agents plus venetoclax versus monotherapy.

Abstract

Supplemental Table 4: Baseline characteristics in HMA-naïve patients with HR-MDS treated with HMA plus venetoclax versus a contemporary HMA monotherapy cohort.

Discussion

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Cite This Study

Bazinet et al. (2024) studied this question.

synapsesocial.com/papers/68e712deb6db64358768bf76 https://doi.org/10.1158/1078-0432.25515448

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