The removal of pathogenic substances by therapeutic plasma exchange (TPE), as a treatment for antibody-mediated rejection in cardiac transplant, has gain a way as a modern medical therapy. A multidisciplinary approach can be taken from TPE, but nephrologist must be the responsible for prescribing this therapy. Membrane filtration with TPE 2000 (Fig. 1), with an effective surface area of 0.35 m2 of polypropylene with ethylene oxide sterilization, targets a large-molecularweight substances present in plasma as immunoglobulin.
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Topete et al. (2024) studied this question.
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