WCN24-1325 mSLAMB DIALYSIS TO POTASSIUM DEPLETE STORED BLOOD FOR POTENTIAL USE IN CHILDREN WITH SEVERE MALARIA ASSOCIATED ACUTE KIDNEY INJURY

Acute kidney injury (AKI) remains a common cause of preventable death in low-middle income countries due to cost and lack of dialysis access. AKI occurs in 24-59% of children with severe malaria (SM-AKI) and worsens mortality. Hyperkalemia, an understudied risk factor, occurs in 6% of Ugandan children with SM; coupled with AKI, mortality approaches 40%. Treatment of these children, especially those with severe anemia, becomes challenging, as packed red blood cells (pRBCs) may have high potassium (K+) loads.