Case report reveals smoldering atypical HUS in familial FSGS, highlighting that renal thrombotic microangiopathy worsens prognosis even when classic hematologic signs are absent.
Thrombocytopenia and MAHA are frequently absent in atypical HUS (aHUS). Thus, renal TMA is easy to miss, especially when a concurrent different renal pathology is more apparent. TMA is, however, associated with worse renal prognosis when superimposed to other pathologies.
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Bassil et al. (2024) studied this question.
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