Diabetic kidney disease (DKD) is a common complication of diabetes mellitus (DM) that may not be diagnosed until later stages of disease. Ways to improve non-invasive screening for DKD are desirable. Kidney cell exfoliation into urine is an active process, which may generate significant information regarding an individual's kidney status. Proximal tubule cell (PTC) exfoliation could also be useful within the DM context as glucose entry into PTCs is insulin independent, making PTCs particularly sensitive to hyperglycemia in diabetic conditions.
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Wu et al. (2024) studied this question.
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