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Fetuin-A is a multifunctional liver-derived protein found in high concentrations in human serum. In end-stage renal disease populations, especially dialysis patients, lower plasma fetuin-A levels are associated with greater prevalence and severity of vascular calcification and increased risk of cardiovascular events and all-cause mortality independent of traditional cardiovascular and kidney disease risk factors. The present study was designed to clarify the precise role and to determine the effectiveness of plasma fetuin-A level as a bioindicator of 3-years of survival and mortality in hemodialysis patients.
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Muzasti et al. (2024) studied this question.
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